In clinical practice, antiepileptic drugs are categorized based on their time of market introduction into older and newer generations. Drugs like valproic acid and those introduced before it are referred to as older or traditional antiepileptic drugs, while those introduced later are termed newer antiepileptic drugs. Recent clinical observations have shown that there is no significant difference in overall efficacy between the older and newer antiepileptic drugs, but the newer drugs generally have a better safety profile. The choice of antiepileptic medication depends on various factors, including the type of seizure, side effects, drug availability, and the patient's age and gender. Traditional antiepileptic drugs include carbamazepine, valproic acid, and phenytoin sodium, while newer ones include levetiracetam, lamotrigine, and topiramate.