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How to Identify Gout Tophi
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Dr. Naina Lalani, MD
700 S Flower StLos Angeles, CA 90017 Internal Medicine
Expert Medical Information
Tophi can be observed in patients with hyperuricemia and gout. Due to impaired purine metabolism leading to excessive uric acid production, urate crystals deposit as fine needle-like structures in soft tissues, causing chronic inflammation and foreign body reactions. This results in fibrous tissue proliferation and the formation of nodules.Tophi are most commonly found in the auricle, possibly due to the slightly acidic blood in this area. They can also appear in the first metatarsophalangeal joint of the toes, as well as in the fingers, wrists, elbows, and knees. In rare cases, they may develop in the nasal cartilage, tongue, vocal cords, eyelids, aorta, heart valves, and myocardium.Tophi near joints can invade bone tissue, leading to skeletal deformities or bone destruction.
Common symptoms include fever, fatigue, and discomfort in the affected area. Always consult with a healthcare professional for an accurate diagnosis.
Diagnosis typically involves a physical examination, medical history review, and possibly laboratory tests or imaging studies depending on the suspected cause.
Treatment options vary based on the specific condition, severity, and individual health factors. They may include medication, lifestyle changes, physical therapy, or in some cases, surgical intervention.
Seek immediate medical attention if you experience severe symptoms, rapid worsening of condition, or if self-care measures aren't providing relief within a reasonable timeframe.