The imaging diagnostic methods for gallstone disease primarily include ultrasound, abdominal X-ray, oral cholecystography, CT, and MRI. Traditional X-ray and oral cholecystography have been less frequently used in recent years due to the low detection rate of abdominal X-rays. While mixed calcium-containing stones may be visible on X-ray, pure cholesterol and pigment stones are not detectable.Oral cholecystography has a high gallbladder visualization rate and can detect stones in the gallbladder and even the extrahepatic bile ducts, but its effectiveness is influenced by various factors.Ultrasound, known for its convenience, non-invasiveness, repeatability, and high diagnostic accuracy, has become the preferred method for diagnosing gallstone disease. Whether it’s gallbladder stones, extrahepatic bile duct stones, or intrahepatic bile duct stones, on ultrasound imaging, stones appear as hyperechoic masses or spots with posterior acoustic shadowing.