The nuchal translucency (NT) measurement, also known as the nuchal fold thickness, is an important screening method for fetal abnormalities during the first trimester. It is typically measured via ultrasound around the 12th week of pregnancy. Under normal circumstances, the NT measurement should be less than 2.5 millimeters. If it exceeds 2.5 millimeters, it is referred to as increased NT, which warrants attention and concern, as it may indicate potential fetal abnormalities. First, if the NT measurement falls between 2.5 and 3.0 millimeters, it is considered borderline increased NT. Generally, the likelihood of fetal abnormalities is low in such cases, and further screening through non-invasive prenatal testing (NIPT) or detailed ultrasound can be conducted to assess for any anomalies. Second, if the NT measurement is above 3.0 millimeters, it is classified as significantly increased NT. In these cases, it is essential to perform amniocentesis and a detailed ultrasound to screen for chromosomal and structural abnormalities in the fetus. The greater the NT measurement, the higher the probability of fetal abnormalities. Therefore, in clinical practice, increased NT must be taken seriously, and definitive diagnostic methods should be employed to rule out fetal abnormalities.