Monocytes are a crucial type of cell in the human body, being the largest white blood cells, while lymphocytes are among the smallest.
Normally, monocytes make up 3% to 8% of the total white blood cell count, whereas lymphocytes account for 20% to 40%.
When the percentage of monocytes is elevated due to certain conditions, there may be a relative decrease in lymphocytes. This can occur in several scenarios:
1. During certain infections such as typhoid, tuberculosis, or malaria, where an elevated monocyte count and reduced lymphocytes may be observed.
2. In the case of certain blood disorders, like monocytic leukemia, where an increase in monocytes and a decrease in lymphocytes might be present.
3. During the recovery phase of acute infectious diseases or acute infections, this pattern can also emerge.