The lifespan of patients with hepatitis B-related cirrhosis primarily depends on the stage of cirrhosis progression, as cirrhosis can be classified into compensated and decompensated stages based on disease severity. In the compensated stage of cirrhosis, liver damage is not severe, and the liver retains its compensatory function, allowing it to perform normal physiological processes. With effective treatment, the condition can be reversed, so it has minimal impact on lifespan.
However, the decompensated stage of cirrhosis is an irreversible pathological process characterized by symptoms such as extreme weight loss, portal hypertension, and complications like massive ascites, upper gastrointestinal bleeding, hepatic encephalopathy, hepatic coma, hepatorenal syndrome, and infections. Consequently, patients in the decompensated stage of cirrhosis have a very short lifespan, typically ranging from six months to about a year.