The treatment principle for acute inferior wall myocardial infarction is to restore myocardial blood perfusion as quickly as possible. This includes initiating thrombolysis within 30 minutes of hospital arrival or performing interventional therapy within 90 minutes to salvage dying myocardium, prevent infarction expansion, reduce the ischemic area, protect and maintain cardiac function, and promptly manage severe arrhythmias, pump failure, and various complications. Upon diagnosis of inferior wall myocardial infarction, patients should immediately take aspirin and clopidogrel orally, and coronary angiography should be arranged as soon as possible. Hospitals without the capability for emergency coronary angiography and stent placement may administer thrombolytic therapy, commonly using drugs such as urokinase or streptokinase. If the time window for emergency coronary angiography or thrombolysis has passed, it is recommended to provide anticoagulation, lipid-lowering, and symptomatic treatment in the cardiac intensive care unit. Coronary angiography should be performed once the patient's condition stabilizes, with stent placement if necessary.